Highly Competitive Performance - High Throughput, Excellent Sample Preservation Rate & Detection Sensitivity
Also known as C2c1, purified from E. coli strain containing the Alicyclobacillus acidophilus Cas12b expression gene. It belongs to the V-type CRISPR Cas system. In the presence of PAM in the target DNA, it is a RNA mediated Nuclease that specifically targets to cut double stranded DNA. The binding of LbCas12b crRNA complex with complementary single stranded DNA or double stranded DNA releases strong non-specific ssDNA transcleavage activity. Compared to Cas13a, Cas12b can maintain higher activity under loop mediated isothermal amplification (LAMP) reaction conditions.
Multiple enzymes work together at room temperature to achieve rapid amplification of nucleic acids, which is a true POCT technology. It is a next-generation high sensitivity, high specificity, fast isothermal Nucleic acid test technology based on CRISPR detection development
